Risk Factors of Shindo et al for Community-Acquired or Healthcare-Associated Pneumonia with a Drug-Resistant Pathogen (DRP)

 

Patient selection: adult with community-acquired and healthcare-associated pneumonia in Japan

 

Risk factors for drug-resistant pathogen causing CAP:

(1) hospitalized >= 2 days in preceding 90 days (3 months)

(2) immunosuppressed (probably also immunocompromised)

(3) therapy with antibiotics in past 90 days

(4) therapy with a drug causing gastric acid suppression

(5) tube feedings

(6) nonambulatory

 

total number of risk factors =

= SUM(number of risk factors present)

 

Interpretation:

• minimum number of risk factors: 0

• maximum number of risk factors: 6

• The risk of a drug-resistant pathogen increases with the number of risk factors present.

 

Number or Risk Factors	Antibiotic Resistance
0	4%
1	9%
2	22%
3	43%
4	54%
5 or 6	83%