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Risk Factors of Saxena et al for Massive Transfusion Associated with Cytoreductive Surgery

Description

Saxena et al identified risk factors for massive blood transfusion associated with cytoreductive surgery. These can help to identify a patient who may require more aggressive management. The authors are from the University of New South Wales in Sydney, Australia.


Patient selection: peritoneal carcinomatosis undergoing cytoreductive surgery with intraperitoneal chemotherapy

 

Outcome: massive allogeneic red blood cell transfusion

 

Risk factors for massive transfusion:

(1) operative length > 9 hours

(2) preoperative hemoglobin < 125 g/L

(3) peritoneal cancer index >= 16

(4) preoperative INR >= 1.2

(5) number of peritonectomy procedures >= 4

 

where:

• Surgery prior to 2004 was also associated with risk of massive transfusion.

 

Several of the factors reflect high tumor burden.


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