Sato et al identified risk factors for an unfavorable outcome after a minor ischemic stroke. These can help to identify a patient who may benefit from more aggressive management. The authors are from the National Cerebral and Cardiovascular Center in Osaka and the Stroke Unit Multicenter Observational (SUMO) Trial.


Patient selection: minor ischemic stroke (NIHSS <= 3), prestroke disability 0 or 1 by modified Rankin scale


Unfavorable outcome: modified Rankin scale 3 to 6 at 90 days


Risk factors associated with an unfavorable outcome:

(1) female gender (OR 2.0)

(2) age >= 72 years (OR 2.8)

(3) leg weakness (OR 1.7)

(4) extinction/inattention (OR 5.6)

(5) intra- and/or extra-cranial vascular occlusion/narrowing (>= 50% narrowing in diameter or occlusion on imaging studies including carotid arteries, OR 2.8)


The risk of an unfavorable outcome increases with the number of risk factors.


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