Risk Factors of Riggio et al for Overt Hepatic Encephalopathy in a Patient with Cirrhosis

Patient selection: cirrhosis

Outcome: overt hepatic encephalopathy within follow-up period (up to 42 months in Figure 1)

Risk factors from multivariate analysis::

(1) previous history of overt hepatic encephalopathy (hazard ratio 2)

(2) evidence of minimal encephalopathy by the psychometric hepatic encephalopathy score (PHES), with a score < -4 (hazard ratio 2)

(3) serum albumin < 3.5 g/dL (hazard ratio 2.3)

Each risk factor was assigned 1 point if present, else 0.

The coefficients for the multivariate model nor reported.

Performance of model:

• The area under the ROC curve was 0.74.