Rautaharju et al identified risk factors in an ECG from a postmenopausal woman that are associated with increased cardiovascular mortality. These can help identify a woman who may benefit from closer monitoring and more aggressive management. The authors are from Wake Forest University in Winston-Salem, North Carolina, and the Fred Hutchinson Cancer Center in Seattle, Washington.
Parameters:
(1) QRS/T wave angle
(2) changes of acute myocardial infarction (AMI)
(3) QRS nondipolar voltage
(4) heart rate variability
(5) QT interval
(6) history of cardiovascular disease
Parameter |
Finding |
Points |
QRS/T wave angle |
0 to 96 degrees |
0 |
|
wide (>= 97 degrees) |
1 |
ECG changes of AMI |
absent |
0 |
|
present |
1 |
QRS nondipolar voltage |
< 65 microvolts |
0 |
|
increased (>= 65 microvolts) |
1 |
heart rate variability |
>= 8 milliseconds |
0 |
|
< 8 milliseconds (low) |
1 |
QT interval and history of cardiovascular disease |
QT interval < 437 milliseconds OR history of cardiovascular disease |
0 |
|
QT interval prolonged (>= 437 milliseconds) AND no history of cardiovascular disease |
1 |
where:
• The odds ratios for the risk factors are in the 1.8 to 2.1 range.
• The risk appears to be from all cause cardiovascular mortality (not just coronary heart disease).
• ECG changes of AMI may range from small to massive infarct, which would affect mortality.
total number of risk factors =
= SUM(points for all 5 risk factors)
Interpretation:
• minimum number of risk factors: 0
• maximum number of risk factors: in theory 5, in practice probably 4
• The risk of cardiovascular mortality increases as the number of risk factors increase.
Specialty: Cardiology, Obstetrics & Gynecology