Patient selection: age >= 18 years with central line catheter
Factors associated with increased risk of CLABSI:
(1) greater number of central line days
(2) kidney disease
(3) beta blocker therapy
(4) diuretics (? related to kidney disease)
where:
• The number of central line days ranged from 2 to 7 for patients without CLABSI (median 4).
• The number of central line days ranged from 4 to 12 for patients with CLABSI (median 5.5).
Factors associated with decreased risk of CLABSI:
(1) myocardial infarction
(2) cholesterol lowering drugs (? related to ischemic heart disease)
(3) antihypertensive therapy
Interestingly scores of comorbidity (Charlson, Chronic Disease Score) were not found to be significant.
Limitations:
• The study was performed at one site.
• The number of CLABSI cases was limited (76 cases).