Pedros et al identified risk factors for hospital admission because of adverse drug reaction (ADR). The authors are from Bellvitge University Hospital, L'Hospitalet de Llobregat, and University of Barcelona in Spain.
Patient selection: hospital admission for adverse drug reaction (ADR)
Frequency: 4% of urgent admissions
Risk factors:
(1) age
(2) number of drugs being taken at the time of hospital admission
Parameter
Findings
Odds Ratio
age
< 65 years
1
>= 65
1.6
number of drugs
<= 2
1
3 to 5
5.1
6 to 9
5.9
>= 10
8.9
Reason for Admission
Implicated Drug
acute renal failure
renin-angiotensin system inhibitors, NSAID, other
gastrointestinal hemorrhage
anticoagulant, NSAID or antiplatelet drug
other hemorrhage
anticoagulant
decreased level of consciousness
benzodiazepines, neuroleptics
atrioventricular block
calcium channel blocker, beta-blocker
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