Needel et al identified risk factors in a plexiform neurofibroma associated with disease progression. This can help identify a patient who may benefit from more aggressive management or a trial of new treatment. The authors are from the Children's Hospital of Philadelphia.
Parameters:
(1) age
(2) location
(3) extent of surgical excision
|
Parameter |
Favorable |
Intermediate |
Unfavorable |
|
age |
>= 10 years of age |
|
< 10 years of age |
|
location |
extremity |
|
head and neck, torso |
|
surgical excision |
complete |
subtotal |
unresected |
Excellent outcome:
(1) age >= 10 years
(2) located on an extremity
(3) completely excised
Poor Outcome:
(1) < 10 years of age
(2) located on head and neck or torso
(3) unresected
|
Age |
Location |
Resection |
Outcome |
|
< 10 years of age |
not extremity |
unresected |
poor |
|
|
|
subtotal |
guarded |
|
|
|
complete |
fair |
|
|
extremity |
unresected |
guarded |
|
|
|
subtotal |
fair |
|
|
|
complete |
good |
|
>= 10 years of age |
not extremity |
unresected |
guarded |
|
|
|
subtotal |
fair |
|
|
|
complete |
good |
|
|
extremity |
unresected |
guarded |
|
|
|
subtotal |
fair |
|
|
|
complete |
excellent |
Specialty: Hematology Oncology, Surgery, general, Surgery, orthopedic
