Morisaki et al reported risk factors for wound complications and 30-day mortality in patients with peripheral arterial disease undergoing a major amputation of a lower extremity. These can help to identify a patient who may require more aggressive management. The authors are from Matsuyama Red Cross Hospital in Japan.


(1) wound complications (dehiscence, surgical site infection)

(2) 30-day morality


Rate of wound complications: 13.3%

Rate of 30-day mortality: 7.6%


Causes of death: pneumonia, sepsis, cardiac death


Risk factors for wound complications:

(1) female sex (HR 4.7)

(2) below-the-knee amputation (HR 4.4)


Risk factors for 30-day mortality:

(1) hypoalbuminemia (HR 3.87)

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