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Risk Factors of Mizota et al for Acute Kidney Injury (AKI) Associated with Major Intra-Abdominal Surgery

Description

Mizota et al identified risk factors associated with acute kidney injury (AKI) associated with major intra-abdominal surgery. These can help to identify a patient who may benefit from more aggressive management. The authors are from Kyoto University.


Patient selection: intra-abdominal surgery

 

Parameters:

(1) AKI risk index of Kheterpal, from 1 to 5

(2) intraoperative blood loss in mL per kilogram

(3) intraoperative vasopressor infusion

(4) intraoperative urine output in mL per kilogram per hour

 

Parameter

Finding

Odds Ratio for AKI

AKI risk index

Class 1

1

 

Class 2

2.3

 

Class 3

3.7

 

Class 4

5.4

 

Class 5

7.4

intraoperative blood loss

< 10 mL per kg

1

 

10 to 19.9 mL per kg

3.2

 

>= 20 mL per kg

6.0

intraoperative vasopressors

no

1

 

yes

1.7

intraoperative urine output

>= 0.3 mL per kg per hour

1

 

< 0.3 mL per kg per hour

2.7

 

where:

• The type of surgery was associated with high p values in 3 of the categories..

 

cumulative odds ratio =

= PRODUCT(all 4 odds ratios)


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