Melboucy-Belkhir et al identified risk factors for intracranial hemorrhage in a patient with immune thrombocytopenic purpura (ITP). These risk factors can help to identify a patient who may benefit from more aggressive management. The authors are from multiple institutions in France.

Patient selection: immune thrombocytopenia


Outcome: intracranial hemorrhage


Risk factors for intracranial hemorrhage:

(1) extracranial life-threatening bleeding

(2) failure to respond to therapy with corticosteroids

(3) presence of one or more precipitating factor (head trauma, intracranial vascular malformation, infection, drug that interferes with hemostasis)


Factors associated with reduced risk:

(1) cutaneous bleeding (mild bleeding)

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