Risk Factors of Marrelli et al for Liver Metastases After Surgical Resection of a Gastric Adenocarcinoma

 

Patient selection: Patients who have undergone a curative surgical resection (negative margins, removal of omentum and regional lymph nodes).

 

Risk factors known shortly after surgery that are associated with liver metastases within 5 years of gastric resection:

(1) metastases to lymph nodes

(2) intestinal histologic pattern (vs diffuse or mixed)

(3) one or more positive serum tumor marker (CEA, CA19-9, or CA72-4) before the surgery

 

where:

• CA19-9 = carbohydrate antigen 19-9.

• CA72-4 = cancer antigen 72-4

 

The presence of elevation in one or more serum tumor markers (CEA, CA19-9, CA72-4) during followup was associated with hepatic metastases.