Louik et al identified risk factors for nausea with or without vomiting in a pregnant woman. The authors are from Boston University.


Nausea during pregnancy:

(1) is common (affecting 50-80% of pregnancies; 67% in current study)

(2) usually starts during the first trimester (early onset)

(3) prevalence peaks between months 2 and 5 of the pregnancy


Risk factors for nausea during pregnancy:

(1) younger age (risk decreases with increasing age; adjusted odds ratio highest when <= 25 years of age, lowest when > 40)

(2) increased gravidity (including miscarriages and abortions)

(3) multiple gestation (twins, triplets, etc.)


Risk factors for onset of nausea after the first trimester (late onset):

(1) Black race

(2) lower level of education

(3) lower income level


Other factors associated with slightly increased risk (Tables 1 and 2)

(1) stopping smoking

(2) presence of a urinary tract infection

(3) presence of pre-eclampsia

(4) presence of oral or genital herpes

(5) presence of vaginal bleeding

(6) presence of obesity


Other factors associated with slightly decreased risk (Tables 1 and 2)

(1) continued smoking during pregnancy

(2) Blacks and Native Americans had lower risk than other racial groups

(3) presence of diabetes

(4) presence of seizures


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