Description

Kollef et al identified risk factors associated with mortality in patients with acute gastrointestinal (GI) hemorrhage. These can help identify patients who may require more aggressive management. The authors are from Washington University in St. Louis.


 

Patient selection: upper and/or lower GI hemorrhage

 

Parameters identified as independent risk factors for mortality on multivariate analysis:

(1) ascites

(2) APACHE III score

(3) Organ System Failure Index of Rubin et al

Parameter

Findings

Points

ascites

absent

0

 

present

1

APACHE III score

<= 30

0

 

> 30

1

organ system failure index

0 or 1

0

 

2 to 7

1

 

where:

• The adjusted odds ratio for ascites was 7.1, for APACHE III score 6.2, and organ system failure index was 4.5. To simplify the analysis a single point was assigned for each parameter.

• The Organ System Failure Index has 1 point assigned for organ failure in 7 systems: renal, hepatic, pulmonary, bone marrow, neurologic, gastrointestinal, and cardiac.

 

total number of factors present =

= SUM(points for all 3 parameters)

 

Interpretation:

• minimum number of risk factors: 0

• maximum number of risk factors: 3

• The risk of mortality increases with the number of parameters.

 


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