Jong et al identified risk factors for fatigue in patients infected with HIV. These can help to identify a patient who may benefit from an intervention to reduce the fatigue. The authors are from multiple universities in The Netherlands.

Patient selection: HIV positive


Risk factors for fatigue:

(1) combined antiretroviral therapy (ART)

(2) effects of other medications

(3) impaired sleep

(4) anxiety and/or depression

(5) other significant comorbid disease including chronic infection


Patients who were fatigued had issues with:

(1) reduced work capacity with risk of unemployment and economic difficulties

(2) decreased social activities with risk of isolation

(3) reduced motivation

(4) impaired ability to mentally concentrate

(5) daytime drowsiness

(6) reduced quality of life


A patient with risk factors for fatigue should be screened for fatigue and the patient's quality of life.

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