Poor outcome:
(1) nephrectomy
(2) death
Risk factors for poor outcome when the patient is admitted to the hospital or at initial presentation:
(1) thrombocytopenia (< 120,000 per µL)
(2) disturbance of consciousness (confusion, delirium, stupor or coma)
(3) shock
(4) severe proteinuria (> 3 grams per liter urine on >= 2 urinalyses during the hospital admission)
(5) acute impairment of renal function
where:
• The definition of severe proteinuria is not measured in output per 24 hours.
• Thrombocytopenia, shock and disturbed consciousness can be seen in Gram negative bacteremia and/or DIC, which may be complicated by multi-organ failure.
• Severe proteinuria may be related to pre-existing glomerulonephritis and diabetic nephropathy,
• Acute impairment of renal function was defined as an elevation of serum creatinine (a) > 0.5 mg/dL if baseline level is < 3 mg/dL or (b) > 1.0 mg/dL if the baseline level is > 3.0 mg/dL
