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Risk Factors of Hu et al for Incisional Surgical Site Infection Following Bowel Resection for Crohn's Disease

Description

Hu et al reported risk factors for incisional (superficial) surgical site infection following bowel resection for Crohn's disease. These can help to identify a patient who may benefit from interventions to reduce these complications. The authors are from the Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Flood Diseases and Guangdong Institute of Gastroenterology in China.


Patient selection: bowel resection for Crohn's disease

 

Outcome: incisional surgical site infection

 

Risk factors for incisional surgical site infection on multivariate analysis:

(1) preoperative anemia (hemoglobin < 120 g/L; odds ratio 3.3)

(2) elevated percentage of neutrophils ( >75%; odds ratio 2.9)

(3) intra-operative finding of fistula (odds ratio 3.8)

 

Table 1 suggests that an elevated white blood cell count (> 10*10^9/L) is associated with SSI. A higher frequency of SSI is associated with penetrating disease (B3).

 

Suggested interventions prior to surgery:

(1) improved nutritional status

(2) reduction in inflammation


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