Risk Factors of Holm et al for Acute Renal Failure in a Severely Burned Patient

Patient selection: burns > 10% body surface area (BSA)

Risk factors for acute renal failure:

(1) greater burned body surface area (mean in study population 48% with range 13 to 95%)

(2) inhalation injury

Early ARF was defined as having an onset within the first 5 days.

(1) myoglobulinuria

(2) hypotension during the resuscitation phase

Late ARF was defined as an onset after 5 days. Late ARF was associated with:

(1) sepsis

(2) therapy with nephrotoxic antibiotics (prescribed for the sepsis)

Most patients who died had multi-organ failure.