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Description

Hasak et al identified factors associated with postfundoplication dysphagia. These can help to identify a patient who may benefit from additional therapy. The authors are from Washington University in Saint Louis.


Patient selection: fundoplication for reflux (antireflux surgery)

 

Dysphagia was considered clinically significant if it was rated 2 or higher on a Likert scale ranging from 0 to 4.

 

Classification of postfundoplication dysphagia:

(1) early-onset: <= 6 weeks after surgery

(2) late-onset: > 6 weeks

 

Early-onset dysphagia usually responds to conservative therapy.

 

Significant late-onset dysphagia often responds to endoscopic dilation.

 

Predictors for late-onset dysphagia on univariate analysis:

(1) dysphagia prior to fundoplication

(2) early-onset postfundoplication dysphagia (??)

(3) recurrent hiatal hernia

(4) lack of contraction reserve following multiple rapid swallows (five 2 mL swallows less than 4 seconds apart)

 

Absence of contraction reserve was defined as a ratio < 1 for (the mean distal contractile integral during multiple rapid swallows) divided by (the distal contractile integral for s single swallow).

 

Lack of contraction reserve was the independent predictor on multivariate analysis with odds ratio 3.7.


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