Harmon et al reported risk factors for infection following a penetrating brain injury. The authors are from the Eastern Association for the Surgery of Trauma.

Patient selection: penetrating brain injury


Infections were both monomicrobial and polymicrobial. Enterococcus and Staphylococcus werre the most common isolates, but many types of bacteria are implicated.


Risk factors for infection:

(1) surgical intervention (OR 2.6)

(2) intracerebral pressure monitor (OR 2.3)


Factors that did not reduce infections:

(1) prophylactic antibiotics


Factors not predictive of infection:

(1) degree of dural penetration

(2) trajectory through the oropharynx


Removal of deep foreign body fragments tends to cause more harm than good, and antibiotic prophylaxis may not be of benefit.

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