Risk Factors of Hampshire et al for In-Hospital Mortality for a Patient with a Hematological Malignancy Admitted to an Intensive Care Unit

 

Patient selection: adult with hematological malignancy admitted to hospital

 

Major risk factors for mortality:

(1) multi-organ failures (70% mortality with 2 organ failures, 100% with 4)

(2) in-hospital for >= 20 days before admission to ICU

(3) anemia with hematocrit < 46%

(4) systolic hypotension (< 50 mm Hg)

(5) Glasgow coma score <= 5

 

Additional risk factors:

(1) history of bone marrow transplant

(2) Hodgkin's disease

(3) sepsis

(4) tachypnea

(5) tachycardia

(6) abnormal arterial pH (acidosis or alkalosis)

(7) abnormal serum sodium (hyper or hyponatremia)

(8) hypoxemia

(9) oliguria

(10) uremia

(11) use of sedation

(12) need for vasopressors

 

where:

• Older age was listed as a risk factor but the data in Table 4 shows a fairly tight clustering for age and percentage of deaths.