Risk Factors of Gray et al for Severe Respiratory Adenovirus Infection

 

NOTE: The paper reports risk factors for severe disease but did not use a risk score.

 

Severe infection was defined as ICU admission or death.

 

Parameters:

(1) age of the patient in years

(2) chronic comorbid disease

(3) recent transplantation

(4) adenovirus type

Parameter	Finding	Points
age of the patient	< 7 years old	0
	>= 7 years old	1
chronic comorbid disease	none	0
	one or more	1
recent transplantation	no	0
	yes	1
adenovirus type	5	1
	21	2
	other	0

 

where:

• The odds ratios for most of the risk factors were 2.7 to 3.6, except for type 21 which was 7.6.

• Other studies have reported risk for type 7.

 

total risk score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum risk score: 0

• maximum risk score: 5

• The higher the score the greater the risk for severe infection.