Description

Garcia-Vidal et al identified risk factors for mortality in patients with acute leukemia who presented with a bloodstream infection. These can help to identify a patient who may benefit from more aggressive therapy. The authors are from multiple institutions in Spain.


Patient selection: acute leukemia with bloodstream infection

 

Outcome: mortality (30-day mortality in the study was 15%)

 

Risk factors:

(1) older age (> 65 years of age)

(2) chronic lung disease

(3) rapidly fatal designation (death expected within 3 months) by the McCabe-Jackson classification

(4) pulmonary infection

(5) multi-drug resistant Pseudomonas aeruginosa with inappropriate therapy

(6) shock at onset

 

The risk for mortality increases with the number of risk factors present.


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