Fu et al evaluated older adults with Acinetobacter baumanii bacteremia in China. They identified risk factors for extensive drug resistance and for mortality. The authors are from FuXing Hospital and Capital Medical University in Beijing.


Patient selection: adult > 65 years of age with Acinetobacter baumanii bacteremia



Resistant to

multidrug (MDR)

>= 3 of the following: aminoglycosides, antipseudomonal penicillin and beta-lactamase inhibitor combination, antipseudomonal carbapenema, antipseudomonal fluoroquinolones, trimethoprim-sulfamethoxazole, cephalosprins, ampicillin-sulbactam, polymyxins, tetracyclines

extensive (XDR)

all of the antibiotics listed above except polymyxins and tigecycline

carbapenem (CR)

imipenem or meropenem


Risk factors for extensive drug resistance:

(1) COPD

(2) bedridden

(3) central venous catheter


Risk factors for mortality:

(1) extensive drug resistance

(2) in the ICU

(3) concurrent fungal infection

(4) age >= 70 years


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