Risk Factors of Frasson et al for Anastomotic Leak After Colon Resection for Cancer

Description

Frasson et al identified risk factors for anastomotic leak in patients undergoing colon resection for cancer. These can help to identify a patient who may benefit from more aggressive or an alternative management. The authors are from multiple hospitals in Spain participating in the ANACO Study Group.

Patient selection: colon resection for colon cancer (excluding rectum)

Outcome: anastomotic leak

Parameters:

(1) therapy with oral anticoagulants

(2) intraoperative complications (bleeding, urinary tract, intestine, anastomotic)

(3) body mass index (BMI)

(4) sex

(5) serum total protein

(6) number of beds in the hospital

Total Protein	Points
< 4	NA
4 to 8	= (-16.75 * (protein)) + 159
> 8	NA

Bed Count	Points
< 100	NA
100 to 1500	=(-0.014714 * (beds)) + 22.07
> 1500	presumably 0

Parameter	Finding	Points
anticoagulation therapy	no	0
	yes	23.2
intraoperative complications	no	0
	yes	33.8
BMI	<= 30 kg per sq m	0
	> 30 kg per sq m	36.8
sex	female	0
	male	24.3

total score =

= SUM(points for all 6 parameters)

Interpretation:

• minimum score: 25

• maximum score: 230.6

• The higher the score the greater the risk for anastomotic leak.

Total Score	Percent Anastomotic Leak
< 56.6	< 5%
56.6 to 192.6	(0.001931((score)^2)) - (0.1497 (score)) + 7.315
> 192.6	> 50%

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Risk Factors of Frasson et al for Anastomotic Leak After Colon Resection for Cancer

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