Elkins et al identified ECG changes associated with short term cardiac morbidity in patients who have had a transient ischemic attack (TIA). These can identify a patient who may benefit from closer monitoring and more aggressive therapy. The authors are from the University of California at San Francisco.
Criteria for cardiac morbidity:
(1) acute myocardial infarction
(2) ventricular arrhythmia
(3) heart failure
(4) unstable angina
Findings on the ECG associated with a cardiac event within 90 days of a TIA:
(1) atrial fibrillation
(2) left ventricular hypertrophy
(3) heart rate > 80 beats per minute
(4) atrioventricular (AV) block
Other findings associated with increased cardiac morbidity:
(5) history of coronary artery disease
(6) systolic blood pressure < 140 mm Hg
Finding |
Odds Ratio |
95% CI |
p value |
atrial fibrillation |
7.2 |
3.0 – 17.0 |
< 0.001 |
LV hypertrophy |
4.5 |
2.1 – 9.7 |
< 0.001 |
heart rate |
4.5 |
2.0 – 10.0 |
0.001 |
AV block |
4.4 |
2.0 – 10.1 |
< 0.001 |
history CAD |
3.7 |
1.6 – 8.0 |
0.001 |
systolic blood pressure |
3.3 |
1.2 – 9.3 |
0.02 |
from Table 3, page 1439
Interpretation:
• A person with none of these findings has less than a 1% chance of short-term cardiac morbidity (based on Table 2, page 1439).
• The presence of 1 or more abnormalities is associated with a 4.2% chance of cardiac morbidity. The type and number of abnormalities determines the risk.
NOTE: While the relative risk for cardiac morbidity is 4 times greater if an abnormality is present, the overall risk is not enormous unless multiple risk factors are present.
Specialty: Cardiology, Neurology