Description

Elkins et al identified ECG changes associated with short term cardiac morbidity in patients who have had a transient ischemic attack (TIA). These can identify a patient who may benefit from closer monitoring and more aggressive therapy. The authors are from the University of California at San Francisco.


 

Criteria for cardiac morbidity:

(1) acute myocardial infarction

(2) ventricular arrhythmia

(3) heart failure

(4) unstable angina

 

Findings on the ECG associated with a cardiac event within 90 days of a TIA:

(1) atrial fibrillation

(2) left ventricular hypertrophy

(3) heart rate > 80 beats per minute

(4) atrioventricular (AV) block

 

Other findings associated with increased cardiac morbidity:

(5) history of coronary artery disease

(6) systolic blood pressure < 140 mm Hg

Finding

Odds Ratio

95% CI

p value

atrial fibrillation

7.2

3.0 – 17.0

< 0.001

LV hypertrophy

4.5

2.1 – 9.7

< 0.001

heart rate

4.5

2.0 – 10.0

0.001

AV block

4.4

2.0 – 10.1

< 0.001

history CAD

3.7

1.6 – 8.0

0.001

systolic blood pressure

3.3

1.2 – 9.3

0.02

from Table 3, page 1439

 

Interpretation:

• A person with none of these findings has less than a 1% chance of short-term cardiac morbidity (based on Table 2, page 1439).

• The presence of 1 or more abnormalities is associated with a 4.2% chance of cardiac morbidity. The type and number of abnormalities determines the risk.

 

NOTE: While the relative risk for cardiac morbidity is 4 times greater if an abnormality is present, the overall risk is not enormous unless multiple risk factors are present.

 


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