Eck et al evaluated critically ill patients with venous thromboembolism. They identified risk factors and determined the significance of this finding. The authors are from multiple institutions in The Netherlands.

Thromboemboli were classified as:

(1) in-hospital pulmonary embolism or lower extremity deep vein thrombosis

(2) in-hospital non-leg deep vein thrombosis


Risk factors for in-hospital pulmonary embolism or lower extremity DVT:

(1) renal replacement therapy (OR 3.5)

(2) respiratory failure (OR 2.0), presumably with mechanical or noninvasive respiratory support

(3) history of previous venous thromboembolism (OR 3.6)


Risk factors for in-hospital non-leg deep vein thrombosis:

(1) central venous catheter (OR 5.4)

(2) infection (OR 2.2)


The presence of any venous thromboembolism was associated with increased 90-day mortality (OR 2.7).

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