Description

Dillon et al identified factors associated with invasive breast carcinoma in a woman with ductal carcinoma in situ (DCIS) identified in a needle core biopsy. These can help identify a woman who should undergo sentinel node biopsy. The authors are from St. Vincent's University Hospital and University College Dublin in Dublin, Ireland.


 

Patient selection: DCIS in core breast biopsy without any evidence of invasive disease

 

Parameters:

(1) diameter of the focus of DCIS in the excision specimen or mammography

(2) mammographic features

Parameter

Finding

Points

diameter of DCIS

< 5 cm

0

 

>= 5 cm

1

mammographic features

calcifications only

0

 

other features present

1

 

where:

• Other mammographic features include mass, architectural distortion, asymmetrical density, asymmetry and increased density (Table I, page 561).

 

number of risk factors for invasive carcinoma =

= SUM(points for both parameters)

 

Interpretation:

• minimum number of risk factors: 0

• maximum number of risk factors: 2

• The higher the number of risk factors the greater the risk of invasive carcinoma.

• A woman at risk for invasive carcinoma should undergo a sentinel lymph node sampling. The authors recommended sentinel node biopsy if either finding is present.

 

NOTE: If the decision to perform a sentinel lymph node waits for the pathology report from the excision, then the patient needs to undergo 3 proceedures (core biopsy, excisional biopsy, sentinel node biopsy). If the size of the lesion is determined from mammography, then the woman could undergo the sentinel node biopsy at the same time as the excision.

 


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