Patient selection: woman receiving radiation therapy for breast cancer
Time course: onset may be within a few years of therapy to decades later
Risk factors for ischemic heart disease:
(1) cancer in the left breast (OR 1.3)
(2) higher mean radiation dose to the heart
(3) past history of ischemic heart disease (OR 6.7)
(4) history of other circulatory disease (OR 1.9)
(5) history of COPD (OR 6.3)
(6) current smoker (OR 1.9)
(7) history of regular analgesic use (OR 1.7)
(8) obesity (BMI >= 30 kg per square meter; OR 1.6)
(9) diabetes (OR 3.2)
(10) not receiving hormone replacement therapy (OR 1.5)
