Patient selection: <= 6 years of age with a urinary tract infection (UTI)
Parameters on multivariate analysis:
(1) race
(2) age
(3) grade of vesicoureteral reflux (VUR)
|
Parameter
|
Finding
|
Points
|
|
race
|
White
|
1
|
|
|
non-White
|
0
|
|
age
|
3 to 5
|
1
|
|
|
< 3, 6
|
0
|
|
grade of vesicoureteral reflux
|
Grade 1 to 3
|
0
|
|
|
Grade 4 or 5
|
1
|
where:
• The hazard ratios range from 2 (race) to 4.4 (VUR).
• The age ranges with increased risk were 3 to 4 years and 4 to 5 years.
total number of risk factors =
= SUM(points for all 3 parameters)
Interpretation:
• minimum number of risk factors: 0
• maximum number of risk factors: 3
• The risk of recurrent infection increases with the number of risk factors identified.
• The use of prophylactic antibiotics did not decrease the risk of recurrent UTI but it did increase the risk of infection with an antibiotic-resistant organism.
