Carobbio et al identified simple risk factors associated with thrombosis in a patient with essential thrombocythemia. These can help identify a patient who may benefit from more aggressive management to prevent thrombosis. The authors are from Ospedali Riuniti di Bergamo and Universita degli Studi di Firenze in Italy.
Outcome: cumulative risk of thrombosis at 20 years from time of diagnosis
Parameters:
(1) risk group based on age and history of thrombosis
(2) baseline white blood cell count
Age at Diagnosis
History of Thrombosis
Risk Group
< 60 years of age
no
low
< 60 years of age
yes
high
>= 60 years of age
no
high
>= 60 years of age
yes
high
Risk Group
Baseline WBC Count
Cumulative Risk of Thrombosis at 20 Years
low
< 8,700 per µL
20%
low
>= 8,700 per µL
55%
high
< 8,700 per µL
39%
high
>= 8,700 per µL
69%
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