Description

Bhargava et al identified risk factors for a patient exposed to a long-term acute care (LTAC) facility becoming colonized with a carbapenem-resistant Enterobacteriaceae. These can help to identify a patient who may benefit from steps to control the pathogen. The authors are from Wayne State University and Detroit Medical Center.


Patient selection for screening:

(1) from long-term acute care facility to hospital

(2) from hospital to long-term care facility

 

Outcome: positive surveillance culture for a carbapenem-resistant Enterobacteriaceae

 

Parameters:

(1) Charlson comorbidity score

(2) immunosuppression

(3) indwelling devices (central vascular catheters, external drains, urinary catheters, external fixators, tracheostomy tube, gastrostomy tube)

(4) prior antibiotic exposure

 

Parameters

Findings

Points

Charlson comorbidity score

0 to 3

0

 

> 3

1 (OR 4.9)

immunosuppression

absent

0

 

present

1 (OR 3.9)

indwelling device

absent

0

 

present

1 (OR 5.2)

prior antibiotic exposure

absent

0

 

present

1 (OR 3.9)

 

total number of risk factors =

= SUM(points for all 4 parameters)

 

Interpretation:

minimum number of risk factors: 0

maximum number of risk factors: 4

The risk of colonization increases with the number of risk factors present.

The prevalence of carbapenem-resistant organisms in the community, the hospital and the LCAT will affect the pre-test probability.


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