Alkim et al identified risk factors for venous thromboembolism in a patient with inflammatory bowel disease (IBD). These can help to identify a patient who may benefit from antithrombotic therapy during periods of increased risk. The authors are from Sisli Hamidiye Etfal Training and Research Hospital in Istanbul.

Patient selection: inflammatory bowel disease (IBD)


A patient with IBD is at increased risk for thromboembolism related to:

(1) disease flare-up and active disease (related to increased inflammation)

(2) surgery

(3) therapy, including corticosteroids

(4) antiphospholipid antibodies


Additional triggers:

(1) immobilization, including long distance air travel

(2) central line

(3) dehydration


Additional risk factors:

(1) familial or hereditary risk factors

(2) obesity

(3) malignancy

(4) hyperhomocysteinemia

(5) increasing age

(6) pregnancy or oral contraceptives in a woman

(7) drugs given for other conditions

(8) smoking


Management decisions related to thromboembolism in a patient with IBD may range from:

(1) avoidance of risk factors

(2) prophylaxis during periods of increased risk

(3) continuous prophylaxis in high risk patients

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