A patient with systemic lupus erythematosus (SLE) may be at increased risk for thrombosis if certain risk factors are present. A patient identified as being at increased risk may benefit from prophylactic therapy.


Risk factors of Tektonidou et al for a patient with antiphospholipid antibodies:

(1) male gender

(2) presence of lupus anticoagulant

(3) consistently positive anticardiolipin antibodies (NOT negative NOR intermittently positive)


Risk factors of Tektonidou et al for a patient without antiphospholipid antibodies:

(1) male gender

(2) hypertension


The risk factors of Tarr et al are similar but included:

(1) a history of thrombosis

(2) presence of all 3 of the following: lupus anticoagulant, antiphospholipid antibodies, anticardiolipin antibodies


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