Certain risk factors are associated with the risk of disease in patients with coccidioidomycosis. The presence of one or more risk factors may indicate the need for earlier or more aggressive therapy.
Author |
Severe Pulmonary Disease |
Disseminated Disease |
Cohen (1982) |
|
renal transplant ABO Group B or AB male new arrival to endemic area |
Galgiani (1993) |
|
HIV infection organ transplant bone marrow transplant immunosuppression pregnancy Filipino Black (possible) Asian, non Filipino (possible) |
Galgiani (2000) |
|
HIV infection organ transplant high dose corticosteroids 3rd trimester pregnancy |
Leake (2000) |
elderly CHF cancer male corticosteroids new arrival |
|
Louie (1999) |
|
ABO Group B or AB HLA Class II DRB1*1301 allele |
Pappagianis (1988) |
diabetes mellitus |
age < 4 or > 60 Filipino Black Asian, non Filipino immunosuppression transplant pregnancy AIDS |
Rosenstein (2001) |
diabetes mellitus smoking annual income < $15,000 elderly |
Black annual income < $15,000 pregnancy |
Risk factors to be used in spreadsheet:
(1) age < 4 or > 60
(2) male gender
(3) organ or bone marrow transplant
(4) immunosuppression, high dose corticosteroids
(5) HIV infection
(6) pregnancy
(7) Black, Filipino, Asian non-Filipino
(8) ABO Group B or AB
(9) diabetes mellitus (insulin-dependent)
(10) new arrival to an endemic area (non-immune)
Specialty: Infectious Diseases