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Description

Retinopathy of Prematurity (ROP) is associated with several risk factors. Neonates with these risk factors may benefit from early ophthalmologic screening and intervention.


 

Gestational age in weeks at birth - recommended screening if <= 28 weeks.

(1) The Royal College of Ophthalmologists recommended screening if gestational age is < 32 weeks (<= 31 weeks)

 

Gestational Age

Percent of Neonates Who Develop ROP

< 28 weeks

> 80%

28 - 31 weeks

60%

 

Birthweight in grams - recommended screening if <= 1,500 grams:

(1) more serious stages of ROP were associated with birthweight < 1,200 grams

 

Birthweight

Percent of Neonates Who Develop ROP

< 750 grams

90%

750 - 999 grams

78%

1,000 - 1,250 grams

47%

 

Neonatal risk factors: may be associated with ROP even if > 32 week gestational age and birthweight > 1,500 grams:

(1) a sick neonate with an unstable clinical course

(2) bronchopulmonary dysplasia

(3) multiple births (usually associated with small birthweight and early delivery)

(4) administered supplemental oxygen (screen if birthweight <= 1,800 grams)

(5) hemorrhagic shock from placental abruption, etc.

 

Maternal risk factors:

(1) essential hypertension prior to pregnancy

 

Racial factors:

(1) Afro-Americans have a 2-fold reduction in risk of progressing to severe disease

 


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