A number of conditions may predispose to phosphate nephropathy by promoting precipitation of calcium phosphate in distal renal tubules and collecting ducts.
The patient should have a phosphate load to the kidney, either as hyperphosphatemia or phosphate administration
(1) inadequate hydration
(2) hypertension and arteriosclerosis
(3) therapy with NSAIDS
(4) therapy with diuretics
(5) therapy with renin-angiotensin inhibitors (reduce renal perfusion and increase bicarbonateuria)
(6) heart failure
(8) female gender
(9) pre-existing renal impairment (associated with impaired phosphate excretion)
(10) bowel obstruction or increased bowel transit time following oral phosphate load
(11) older age (>= 58 years of age)
To read more or access our algorithms and calculators, please log in or register.
Specialty: Nephrology, Clinical Laboratory