Peptic ulcer disease may develop in people with one or more risk factors. Control of the risk factors may be necessary to get control of the ulcer disease.


Factors increasing the risk of peptic ulcer disease:

(1) infection with Helicobacter pylori

(2) other forms of gastritis

(3) chronic NSAID therapy

(4) cigarette smoking

(5) heavy intake of hard liquor

(6) physiologic stress

(7) psychological stress

(8) gastrinoma

(9) high dose corticosteroids

(10) history of high dose radiation therapy

(11) hepatic arterial infusion chemotherapy

(12) chronic cocaine abuse


Factors decreasing the risk of peptic ulcer disease:

(1) moderate exercise

(2) medication to reduce gastric acid production

(3) diet rich in fiber and fresh vegetables


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