Hernandez-Jiminez et al reported risk factors for infection by multidrug resistant Pseudomonas aeruginosa in an immunocompromised patient. These can help to identify a patient who may require more aggressive management. The authors are from multiple institutions in Spain.
Patient selection: immunocompromised patient
Outcome: infection with multidrug resistant Pseudomonas aeruginosa
Risk factors for infection by a multidrug resistant strain:
(1) diabetes mellitus (OR 4.7)
(2) history of colonization by multidrug resistant Pseudomonas aeruginosa (OR 42.1)
(3) recent receipt of antibiotics (within past 3 months, OR 5.3)
(4) septic shock (OR 3.7)
Infection with a multidrug resistant strain of Pseudomonas aeruginosa is associated with a worse prognosis than for antibiotic-susceptible strains.
If risk factors for a multidrug resistant strain are present, then greater care should be taken to select the appropriate antibiotic to try.
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