Risk Factors for Methotrexate Hepatotoxicity

Are you evaluating a patient who is receiving methotrexate therapy?

Yes

Features of methotrexate therapy

Daily dosing schedule?

Yes

Duration of therapy

years

Total cumulative dose

Maximum weekly dose

Does the patient have?

• renal insufficiency?

Yes

• obesity ?

Yes

• diabetes mellitus?

Yes

• pre-existing liver disease?

Yes

• previous or concurrent heavy ethanol use?

Yes

• heterozygous alpha-1 antitrypsin deficiency?

Yes

• Felty's syndrome?

Yes

Has the patient received the following therapy?

• concurrent NSAID use?

Yes

• concurrent cyclosporine therapy?

Yes

• concurrent PUVA therapy?

Yes

• previous therapy with vitamin A?

Yes

• previous therapy with arsenicals?

Yes

Evaluation

Results

Please fill out required fields.

MedicalAlgorithms.com APIs

Power Your Solutions with 5,000+ Automated Medical Analytics

Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Therapy

Specialty

Objective

ICD-10

Purpose: To evaluate a patient taking methotrexate for risk factors associated with hepatoxicity.