Gastroschisis is a rare disorder which may occur more frequently in infants of mothers with certain risk factors present.


Risk factors in mothers of infants with gastroschisis:

(1) maternal age < 20 years of age

(2) first or second pregnancy (low parity)

(3) low socioeconomic status

(4) social instability

(5) use of aspirin, acetaminophen or ibuprofen (and probably other NSAIDs) during the first trimester

(6) use of pseudoephedrine during the first trimester

(7) alcohol abuse

(8) cigarette use

(9) recreational drug use, especially cocaine



• Some of these risk factors should be linked, being more common in certain population subgroups.


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