Disseminated intravascular coagulation (DIC) may occur in a trauma patient following one or more precipitating events. Identification and correction of the underlying causes is important for the management of the DIC.


Tissue necrosis:

(1) crush injury

(2) brain necrosis

(3) lung necrosis, including pulmonary embolism

(4) acute hepatic injury

(5) rhabdomyolysis

(6) ischemia or vascular injury/surgery

(7) burns

(8) pancreatitis


Hypotension related

(1) shock, including use of an aortic balloon pump

(2) multi-organ failure


Concurrent conditions:

(1) pregnancy

(2) hepatic cirrhosis


Miscellaneous injury:

(1) hypothermia or hyperthermia/heat stroke

(2) asphyxia, hypoxia, or inhalation injury

(3) hemolytic transfusion reaction

(4) massive amniotic fluid, fat or air embolism

(5) near drowning


A patient with one or more of these conditions plus clinical signs of bleeding should be screened for DIC.


To read more or access our algorithms and calculators, please log in or register.