Some patients develop deep vein thrombosis after splenectomy. The presence of several factors may increase the risk.
The portal vein is a common site for thrombosis but other veins may be affected. Patients may be at increased risk for pulmonary embolism and stroke.
Risk factors for postsplenectomy thrombosis:
(1) splenomegaly (Stamou et al reported risk when spleen > 650 grams)
(2) thrombocytosis after surgery
(3) hemolytic anemia
(4) thrombophilia disorder
(5) possibly female gender
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Specialty: Hematology Oncology