Description

Fungi may colonize the eye during transient fungemia in susceptible patients. This may be initially asymptomatic but later can progress to cause significant morbidity and even blindness. Any patient at risk should be screened for retinal lesions, especially when a deep fungal infection is suspected.


 

Fungi causing endophtalmitis as an opportunistic infection:

(1) Candida albicans

(2) other Candida species

(3) Aspergillus species

(4) other fungi

 

Patients at risk:

(1) cancer patients

(2) organ transplantation

(3) premature infants

(4) congenital or acquired neutropenia

(5) prolonged use of broad-spectrum antibiotics

(6) corticosteroid therapy

(7) immunosuppressive therapy

(8) malnutrition

(9) chronic debilitation

(10) hyperalimentation

(11) indwelling central venous catheters

(12) congenital or acquired immunodeficiency

 

The retinal lesions may consist of focal, round, fluffy, glistening yellow-white areas with indistinct margins. These may found in the posterior pole or at the retinal periphery.

 

Blood cultures are insensitive since fungemia may be transient.

 

Complications may include:

(1) retinal necrosis

(2) vitreous organization

(3) traction retinal detachment

(4) decreased visual acuity up to blindness

 


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