Fungi causing endophtalmitis as an opportunistic infection:
(1) Candida albicans
(2) other Candida species
(3) Aspergillus species
(4) other fungi
Patients at risk:
(1) cancer patients
(2) organ transplantation
(3) premature infants
(4) congenital or acquired neutropenia
(5) prolonged use of broad-spectrum antibiotics
(6) corticosteroid therapy
(7) immunosuppressive therapy
(8) malnutrition
(9) chronic debilitation
(10) hyperalimentation
(11) indwelling central venous catheters
(12) congenital or acquired immunodeficiency
The retinal lesions may consist of focal, round, fluffy, glistening yellow-white areas with indistinct margins. These may found in the posterior pole or at the retinal periphery.
Blood cultures are insensitive since fungemia may be transient.
Complications may include:
(1) retinal necrosis
(2) vitreous organization
(3) traction retinal detachment
(4) decreased visual acuity up to blindness