The Seventh International Conference on Adjuvant Therapy of Primary Breast Cancer held in 2001 at St. Gallen, Switzerland, revised the risk categories for women with breast cancer and negative lymph nodes.
Parameters:
(1) estrogen and progesterone receptors
(2) diameter of invasive tumor in centimeters
(3) histologic or nuclear grade
(4) age of the patient
|
Parameters |
Findings |
Points |
|
maximum tumor diameter |
<= 2 cm |
0 |
|
|
> 2 cm |
1 |
|
histologic or nuclear grade |
Grade 1 |
0 |
|
|
Grade 2 or 3 |
1 |
|
age of the patient |
>= 35 years of age |
0 |
|
|
< 35 years of age |
1 |
number of risk factors =
= SUM(points for all 3 nonreceptor risk factors)
|
Receptor Status |
Other Risk Factors |
Category |
|
one or both positive |
none |
minimal or low risk, endocrine responsive |
|
one or both positive |
one or more |
average or high risk, endocrine responsive |
|
both negative |
NA |
average or high risk, endocrine nonresponsive |
Differences from the 1998 St Gallen criteria:
(1) distinction of endocrine responsive and nonresponsive
(2) clarification of histologic/nuclear grade categories
(3) combining average and high risk into 1 group
Specialty: Hematology Oncology, Surgery, general, Obstetrics & Gynecology
