A patient with diabetic ketoacidosis may develop rhabdomyolysis.

Patient selection: diabetic ketoacidosis


It has been estimated that rhabdomyolysis may be present in 10% of patients with DKA.


Risk factors for rhabdomyolysis may include:

(1) trauma

(2) hyperosmolar state

(3) acidosis

(4) hypophosphatemia

(5) hypernatremia


Clinical features:

(1) The patient may complain of muscle pain or weakness.

(2) Myoglobinuria may be absent.


Laboratory findings:

(1) elevated serum CK (usually > 5 times the upper limit of normal)


The rhabdomyolysis may underly or contribute to acute renal failure.

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