Description

Eloubeidi et al developed a revised TNM classification for esophageal carcinoma. This incorporates tumor length, number of positive lymph nodes and other pathologic findings to stage the tumor. The authors are from the University of Alabama and the Medical University of South Carolina.


 

Group

Findings

Code

T

tumor cannot be assessed

Tx

 

no evidence of primary tumor

T0

 

carcinoma in situ

Tis

 

tumor invades lamina propria or submucosa

T1

 

tumor invades muscularis propria

T2

 

tumor invades adventitia

T3

 

tumor invades adjacent structures

T4

T subcode

length <= 3 cm

a

 

length > 3 cm

b

N

regional lymph nodes cannot be assessed

Nx

 

no regional lymph node metastasis

N0

 

regional lymph node metastases, 1 – 5

N1a

 

regional lymph node metastases, > 5

N1b

M

distant metastasis cannot be assessed

Mx

 

no distant metastasis

M0

 

distant metastasis

M1

from Table 7, page 1442

 

Segment of Esophagus

Distant Metastasis

Designation

upper thoracic

to cervical lymph nodes

M1a

 

to other distant sites

M1b

midthoracic

NA

M1a

 

nonregional lymph nodes and/or other distant sites

M1b

lower thoracic

to celiac lymph nodes

M1a

 

to other distant sites

M1b

 

 

mortality risk based on tumor size in cm =

= 1 – (0.942 * EXP(Y))

 

where:

 

Y =

= (0.021 * ((diameter in cm)^2)) – (0.3285 * (diameter in cm))

 


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