Leise et al reported several revisions to MELD (model for end-stage liver disease) which optimize the prediction of short-mortality for patients awaiting liver transplant. The authors are from the Mayo Clinic.
Patient selection: liver transplantation waiting list
Outcome: 90-day mortality
Parameters:
(1) serum total bilirubin in mg/dL
(2) serum creatinine in mg/dL
(3) INR
Constraints on parameters:
(1) minimum bilirubin: 1 mg/dL
(2) minimum creatinine: 0.8 mg/dL
(3) maximum creatinine: 3 mg/dL
(4) minimum INR 1
(5) maximum INR: 3
Other adjustments: renal replacement therapy defined as creatinine of 3 mg/dL