The Wyburn Mason Syndrome involves arteriovenous malformations (AVM) in retinal and other blood vessels of the head and neck.
Sites for AVM – usually unilateral:
(1) retina (Type III AVM)
(2) mandible
(3) maxilla
(4) intracranial (midbrain, other)
(5) retro-bulbar
(6) facial angiomas
Ocular findings:
(1) poor vision in affected eye
(2) proptosis (secondary to AVM in retrobulbar soft tissue
(3) homonymous hemianopia (if optic tract involved)
Other findings:
(1) neurologic signs (pyramidal, other), depending on CNS involvement
