Barbui and other members of the European LeukemiaNet listed response criteria following therapy for polycythemia vera. The authors are from multiple hospitals in Europe participating in the European LeukemiaNet.
Patient selection: polycythemia vera following therapy
Parameters:
(1) hematocrit without phlebotomy
(2) platelet count
(3) white blood cell count
(4) size of the spleen on imaging
(5) disease-related symptoms
|
Parameter |
Finding |
Points |
|
hematocrit without phlebotomy |
< 45% |
1 |
|
|
>= 45% |
0 |
|
platelet count |
<= 400,000 per µL |
1 |
|
|
> 400,000 per µL |
0 |
|
white blood cell count |
<= 10,000 per µL |
1 |
|
|
> 10,000 per µL |
0 |
|
size of spleen |
normal |
1 |
|
|
enlarged |
0 |
|
disease-related symptoms |
none |
1 |
|
|
any |
0 |
total number of favorable findings =
= SUM(points for all 5 parameters)
|
Findings |
Response |
|
all 5 favorable findings |
complete |
|
3 or 4 favorable findings |
partial |
|
hematocrit < 45% without phlebotomy |
partial |
|
any other pattern |
no response |
Specialty: Hematology Oncology
ICD-10: ,
